… CpG ODN to act as adjuvants in animal models of immune deficiency triggered interest in
their potential to improve the response of geriatric animals … an adjuvant for sc immunotherapy …

… and synthetic DNA containing unmethylated CpG motifs. … ) are ideal agents for cancer
immunotherapy. As reported previously, … that synthetic CpGs are superb vaccine adjuvants in both …

… Citation30 CpG oligodeoxynucleotide (ODN) is a short single… other prokaryotes, but not in
vertebrate genomes. When this … idea, using CpG DNA not only as the immune adjuvant, but …

… the development of CpG-based immunotherapy will certainly … the potency of CpG DNA as
an adjuvant. Nishikawa's group … from four or six oligonucleotides, show promising efficacy in …

… the use of nucleic acids and oligonucleotides in cancer … played a critical role in their immune
adjuvant activity [81]. … memory that protected surviving animals from tumor rechallenge. The …

… adjuvants for different species. This study revealed that … synthetic CpG-dideoxynucleotides-containing
DNA (CpG-DNA). … and TLR9 from other domestic animals including sheep, goat, …

… commonly used immunotherapeutic and vaccine adjuvant, but … have shown that CpG-containing
oligonucleotides can increase … , tissues, organs and animals, there is still a considerable …

… expression is suppressed in vertebrate DNA but is common in … motif-containing
oligodeoxynucleotide (CpG ODN) has … with adjuvant activity self-assembled into nanoparticles for …

… containing three CpG motifs (TLR9 agonist) as adjuvant 2 (… collected from the vaccinated
animals and analysed for the … loop oligonucleotides were each mixed with rectangular DNA …

… CpG oligodeoxynucleotides (CpG-C ODNs), possessing the features of both A type and B
type CpG … demonstrated as an effective antitumor immunotherapy. Based on the structural …